Domecino Ghirlandaio's first major commissioned works were the two frescoes of scenes from the life of St. Fina. In 1481–82 Ghirlandaio received an important commission in the Vatican for a fresco, representing the calling of the first Apostles, Peter and Andrew, in the Sistine Chapel. Ghirlandaio is regarded as one of the most eloquent and elegant narrators of 15th-century Florentine society.
